Neuramate
Brand names,
Neuramate
Analogs
Neuramate
Brand Names Mixture
Neuramate
Chemical_Formula
C20H23NS
Neuramate
RX_link
No information avaliable
Neuramate
fda sheet
Neuramate
msds (material safety sheet)
Neuramate
Synthesis Reference
No information avaliable
Neuramate
Molecular Weight
309.469 g/mol
Neuramate
Melting Point
< 25 oC
Neuramate
H2O Solubility
Soluble as HCl salt
Neuramate
State
Liquid
Neuramate
LogP
5.7
Neuramate
Dosage Forms
Tablets (oral, 1 mg)
Neuramate
Indication
Used for the symptomatic treatment of parkinsonism.
Neuramate
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Neuramate
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Neuramate
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Neuramate
Patient Information
Neuramate
Organisms Affected
Humans and other mammals