Meptran
Brand names,
Meptran
Analogs
Meptran
Brand Names Mixture
Meptran
Chemical_Formula
C20H23NS
Meptran
RX_link
No information avaliable
Meptran
fda sheet
Meptran
msds (material safety sheet)
Meptran
Synthesis Reference
No information avaliable
Meptran
Molecular Weight
309.469 g/mol
Meptran
Melting Point
< 25 oC
Meptran
H2O Solubility
Soluble as HCl salt
Meptran
State
Liquid
Meptran
LogP
5.7
Meptran
Dosage Forms
Tablets (oral, 1 mg)
Meptran
Indication
Used for the symptomatic treatment of parkinsonism.
Meptran
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meptran
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meptran
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meptran
Patient Information
Meptran
Organisms Affected
Humans and other mammals