Gadexyl
Brand names,
Gadexyl
Analogs
Gadexyl
Brand Names Mixture
Gadexyl
Chemical_Formula
C20H23NS
Gadexyl
RX_link
No information avaliable
Gadexyl
fda sheet
Gadexyl
msds (material safety sheet)
Gadexyl
Synthesis Reference
No information avaliable
Gadexyl
Molecular Weight
309.469 g/mol
Gadexyl
Melting Point
< 25 oC
Gadexyl
H2O Solubility
Soluble as HCl salt
Gadexyl
State
Liquid
Gadexyl
LogP
5.7
Gadexyl
Dosage Forms
Tablets (oral, 1 mg)
Gadexyl
Indication
Used for the symptomatic treatment of parkinsonism.
Gadexyl
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Gadexyl
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Gadexyl
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Gadexyl
Patient Information
Gadexyl
Organisms Affected
Humans and other mammals