Pertranquil
Brand names,
Pertranquil
Analogs
Pertranquil
Brand Names Mixture
Pertranquil
Chemical_Formula
C20H23NS
Pertranquil
RX_link
No information avaliable
Pertranquil
fda sheet
Pertranquil
msds (material safety sheet)
Pertranquil
Synthesis Reference
No information avaliable
Pertranquil
Molecular Weight
309.469 g/mol
Pertranquil
Melting Point
< 25 oC
Pertranquil
H2O Solubility
Soluble as HCl salt
Pertranquil
State
Liquid
Pertranquil
LogP
5.7
Pertranquil
Dosage Forms
Tablets (oral, 1 mg)
Pertranquil
Indication
Used for the symptomatic treatment of parkinsonism.
Pertranquil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Pertranquil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Pertranquil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Pertranquil
Patient Information
Pertranquil
Organisms Affected
Humans and other mammals