Quanane
Brand names,
Quanane
Analogs
Quanane
Brand Names Mixture
Quanane
Chemical_Formula
C20H23NS
Quanane
RX_link
No information avaliable
Quanane
fda sheet
Quanane
msds (material safety sheet)
Quanane
Synthesis Reference
No information avaliable
Quanane
Molecular Weight
309.469 g/mol
Quanane
Melting Point
< 25 oC
Quanane
H2O Solubility
Soluble as HCl salt
Quanane
State
Liquid
Quanane
LogP
5.7
Quanane
Dosage Forms
Tablets (oral, 1 mg)
Quanane
Indication
Used for the symptomatic treatment of parkinsonism.
Quanane
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Quanane
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Quanane
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Quanane
Patient Information
Quanane
Organisms Affected
Humans and other mammals