Mepavlon
Brand names,
Mepavlon
Analogs
Mepavlon
Brand Names Mixture
Mepavlon
Chemical_Formula
C20H23NS
Mepavlon
RX_link
No information avaliable
Mepavlon
fda sheet
Mepavlon
msds (material safety sheet)
Mepavlon
Synthesis Reference
No information avaliable
Mepavlon
Molecular Weight
309.469 g/mol
Mepavlon
Melting Point
< 25 oC
Mepavlon
H2O Solubility
Soluble as HCl salt
Mepavlon
State
Liquid
Mepavlon
LogP
5.7
Mepavlon
Dosage Forms
Tablets (oral, 1 mg)
Mepavlon
Indication
Used for the symptomatic treatment of parkinsonism.
Mepavlon
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mepavlon
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mepavlon
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mepavlon
Patient Information
Mepavlon
Organisms Affected
Humans and other mammals