Milprem-400
Brand names,
Milprem-400
Analogs
Milprem-400
Brand Names Mixture
Milprem-400
Chemical_Formula
C20H23NS
Milprem-400
RX_link
No information avaliable
Milprem-400
fda sheet
Milprem-400
msds (material safety sheet)
Milprem-400
Synthesis Reference
No information avaliable
Milprem-400
Molecular Weight
309.469 g/mol
Milprem-400
Melting Point
< 25 oC
Milprem-400
H2O Solubility
Soluble as HCl salt
Milprem-400
State
Liquid
Milprem-400
LogP
5.7
Milprem-400
Dosage Forms
Tablets (oral, 1 mg)
Milprem-400
Indication
Used for the symptomatic treatment of parkinsonism.
Milprem-400
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Milprem-400
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Milprem-400
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Milprem-400
Patient Information
Milprem-400
Organisms Affected
Humans and other mammals