Trankvilan
Brand names,
Trankvilan
Analogs
Trankvilan
Brand Names Mixture
Trankvilan
Chemical_Formula
C20H23NS
Trankvilan
RX_link
No information avaliable
Trankvilan
fda sheet
Trankvilan
msds (material safety sheet)
Trankvilan
Synthesis Reference
No information avaliable
Trankvilan
Molecular Weight
309.469 g/mol
Trankvilan
Melting Point
< 25 oC
Trankvilan
H2O Solubility
Soluble as HCl salt
Trankvilan
State
Liquid
Trankvilan
LogP
5.7
Trankvilan
Dosage Forms
Tablets (oral, 1 mg)
Trankvilan
Indication
Used for the symptomatic treatment of parkinsonism.
Trankvilan
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Trankvilan
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Trankvilan
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Trankvilan
Patient Information
Trankvilan
Organisms Affected
Humans and other mammals