Ataraxine
Brand names,
Ataraxine
Analogs
Ataraxine
Brand Names Mixture
Ataraxine
Chemical_Formula
C20H23NS
Ataraxine
RX_link
No information avaliable
Ataraxine
fda sheet
Ataraxine
msds (material safety sheet)
Ataraxine
Synthesis Reference
No information avaliable
Ataraxine
Molecular Weight
309.469 g/mol
Ataraxine
Melting Point
< 25 oC
Ataraxine
H2O Solubility
Soluble as HCl salt
Ataraxine
State
Liquid
Ataraxine
LogP
5.7
Ataraxine
Dosage Forms
Tablets (oral, 1 mg)
Ataraxine
Indication
Used for the symptomatic treatment of parkinsonism.
Ataraxine
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Ataraxine
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Ataraxine
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Ataraxine
Patient Information
Ataraxine
Organisms Affected
Humans and other mammals