Meprosin
Brand names,
Meprosin
Analogs
Meprosin
Brand Names Mixture
Meprosin
Chemical_Formula
C20H23NS
Meprosin
RX_link
No information avaliable
Meprosin
fda sheet
Meprosin
msds (material safety sheet)
Meprosin
Synthesis Reference
No information avaliable
Meprosin
Molecular Weight
309.469 g/mol
Meprosin
Melting Point
< 25 oC
Meprosin
H2O Solubility
Soluble as HCl salt
Meprosin
State
Liquid
Meprosin
LogP
5.7
Meprosin
Dosage Forms
Tablets (oral, 1 mg)
Meprosin
Indication
Used for the symptomatic treatment of parkinsonism.
Meprosin
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprosin
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprosin
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprosin
Patient Information
Meprosin
Organisms Affected
Humans and other mammals