Anastress
Brand names,
Anastress
Analogs
Anastress
Brand Names Mixture
Anastress
Chemical_Formula
C20H23NS
Anastress
RX_link
No information avaliable
Anastress
fda sheet
Anastress
msds (material safety sheet)
Anastress
Synthesis Reference
No information avaliable
Anastress
Molecular Weight
309.469 g/mol
Anastress
Melting Point
< 25 oC
Anastress
H2O Solubility
Soluble as HCl salt
Anastress
State
Liquid
Anastress
LogP
5.7
Anastress
Dosage Forms
Tablets (oral, 1 mg)
Anastress
Indication
Used for the symptomatic treatment of parkinsonism.
Anastress
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Anastress
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Anastress
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Anastress
Patient Information
Anastress
Organisms Affected
Humans and other mammals