Ansiatan
Brand names,
Ansiatan
Analogs
Ansiatan
Brand Names Mixture
Ansiatan
Chemical_Formula
C20H23NS
Ansiatan
RX_link
No information avaliable
Ansiatan
fda sheet
Ansiatan
msds (material safety sheet)
Ansiatan
Synthesis Reference
No information avaliable
Ansiatan
Molecular Weight
309.469 g/mol
Ansiatan
Melting Point
< 25 oC
Ansiatan
H2O Solubility
Soluble as HCl salt
Ansiatan
State
Liquid
Ansiatan
LogP
5.7
Ansiatan
Dosage Forms
Tablets (oral, 1 mg)
Ansiatan
Indication
Used for the symptomatic treatment of parkinsonism.
Ansiatan
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Ansiatan
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Ansiatan
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Ansiatan
Patient Information
Ansiatan
Organisms Affected
Humans and other mammals