Ecuanil
Brand names,
Ecuanil
Analogs
Ecuanil
Brand Names Mixture
Ecuanil
Chemical_Formula
C20H23NS
Ecuanil
RX_link
No information avaliable
Ecuanil
fda sheet
Ecuanil
msds (material safety sheet)
Ecuanil
Synthesis Reference
No information avaliable
Ecuanil
Molecular Weight
309.469 g/mol
Ecuanil
Melting Point
< 25 oC
Ecuanil
H2O Solubility
Soluble as HCl salt
Ecuanil
State
Liquid
Ecuanil
LogP
5.7
Ecuanil
Dosage Forms
Tablets (oral, 1 mg)
Ecuanil
Indication
Used for the symptomatic treatment of parkinsonism.
Ecuanil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Ecuanil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Ecuanil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Ecuanil
Patient Information
Ecuanil
Organisms Affected
Humans and other mammals