Dormabrol
Brand names,
Dormabrol
Analogs
Dormabrol
Brand Names Mixture
Dormabrol
Chemical_Formula
C20H23NS
Dormabrol
RX_link
No information avaliable
Dormabrol
fda sheet
Dormabrol
msds (material safety sheet)
Dormabrol
Synthesis Reference
No information avaliable
Dormabrol
Molecular Weight
309.469 g/mol
Dormabrol
Melting Point
< 25 oC
Dormabrol
H2O Solubility
Soluble as HCl salt
Dormabrol
State
Liquid
Dormabrol
LogP
5.7
Dormabrol
Dosage Forms
Tablets (oral, 1 mg)
Dormabrol
Indication
Used for the symptomatic treatment of parkinsonism.
Dormabrol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Dormabrol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Dormabrol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Dormabrol
Patient Information
Dormabrol
Organisms Affected
Humans and other mammals