Paxin
Brand names,
Paxin
Analogs
Paxin
Brand Names Mixture
Paxin
Chemical_Formula
C20H23NS
Paxin
RX_link
No information avaliable
Paxin
fda sheet
Paxin
msds (material safety sheet)
Paxin
Synthesis Reference
No information avaliable
Paxin
Molecular Weight
309.469 g/mol
Paxin
Melting Point
< 25 oC
Paxin
H2O Solubility
Soluble as HCl salt
Paxin
State
Liquid
Paxin
LogP
5.7
Paxin
Dosage Forms
Tablets (oral, 1 mg)
Paxin
Indication
Used for the symptomatic treatment of parkinsonism.
Paxin
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Paxin
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Paxin
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Paxin
Patient Information
Paxin
Organisms Affected
Humans and other mammals