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Kessobamate Brand names, Kessobamate Analogs

Kessobamate Brand Names Mixture

  • No information avaliable

Kessobamate Chemical_Formula


Kessobamate RX_link

No information avaliable

Kessobamate fda sheet

Kessobamate msds (material safety sheet)

Kessobamate Synthesis Reference

No information avaliable

Kessobamate Molecular Weight

309.469 g/mol

Kessobamate Melting Point

< 25 oC

Kessobamate H2O Solubility

Soluble as HCl salt

Kessobamate State


Kessobamate LogP


Kessobamate Dosage Forms

Tablets (oral, 1 mg)

Kessobamate Indication

Used for the symptomatic treatment of parkinsonism.

Kessobamate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Kessobamate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Kessobamate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Kessobamate Patient Information

Kessobamate Organisms Affected

Humans and other mammals