Larten
Brand names,
Larten
Analogs
Larten
Brand Names Mixture
Larten
Chemical_Formula
C20H23NS
Larten
RX_link
No information avaliable
Larten
fda sheet
Larten
msds (material safety sheet)
Larten
Synthesis Reference
No information avaliable
Larten
Molecular Weight
309.469 g/mol
Larten
Melting Point
< 25 oC
Larten
H2O Solubility
Soluble as HCl salt
Larten
State
Liquid
Larten
LogP
5.7
Larten
Dosage Forms
Tablets (oral, 1 mg)
Larten
Indication
Used for the symptomatic treatment of parkinsonism.
Larten
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Larten
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Larten
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Larten
Patient Information
Larten
Organisms Affected
Humans and other mammals