Meproban

Meproban Brand names, Meproban Analogs

Meproban Brand Names Mixture

No information avaliable

Meproban Chemical_Formula

C₂₀H₂₃NS

Meproban RX_link

No information avaliable

Meproban fda sheet

Meproban msds (material safety sheet)

Meproban Synthesis Reference

No information avaliable

Meproban Molecular Weight

309.469 g/mol

Meproban Melting Point

< 25 ^oC

Meproban H₂O Solubility

Soluble as HCl salt

Meproban State

Liquid

Meproban LogP

5.7

Meproban Dosage Forms

Tablets (oral, 1 mg)

Meproban Indication

Used for the symptomatic treatment of parkinsonism.

Meproban Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Meproban Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Meproban side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Meproban Patient Information

Meproban Organisms Affected

Humans and other mammals