Meprosa
Brand names,
Meprosa
Analogs
Meprosa
Brand Names Mixture
Meprosa
Chemical_Formula
C20H23NS
Meprosa
RX_link
No information avaliable
Meprosa
fda sheet
Meprosa
msds (material safety sheet)
Meprosa
Synthesis Reference
No information avaliable
Meprosa
Molecular Weight
309.469 g/mol
Meprosa
Melting Point
< 25 oC
Meprosa
H2O Solubility
Soluble as HCl salt
Meprosa
State
Liquid
Meprosa
LogP
5.7
Meprosa
Dosage Forms
Tablets (oral, 1 mg)
Meprosa
Indication
Used for the symptomatic treatment of parkinsonism.
Meprosa
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprosa
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprosa
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprosa
Patient Information
Meprosa
Organisms Affected
Humans and other mammals