Meprol
Brand names,
Meprol
Analogs
Meprol
Brand Names Mixture
Meprol
Chemical_Formula
C20H23NS
Meprol
RX_link
No information avaliable
Meprol
fda sheet
Meprol
msds (material safety sheet)
Meprol
Synthesis Reference
No information avaliable
Meprol
Molecular Weight
309.469 g/mol
Meprol
Melting Point
< 25 oC
Meprol
H2O Solubility
Soluble as HCl salt
Meprol
State
Liquid
Meprol
LogP
5.7
Meprol
Dosage Forms
Tablets (oral, 1 mg)
Meprol
Indication
Used for the symptomatic treatment of parkinsonism.
Meprol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprol
Patient Information
Meprol
Organisms Affected
Humans and other mammals