Mepamtin

Mepamtin Brand names, Mepamtin Analogs

Mepamtin Brand Names Mixture

No information avaliable

Mepamtin Chemical_Formula

C₂₀H₂₃NS

Mepamtin RX_link

No information avaliable

Mepamtin fda sheet

Mepamtin msds (material safety sheet)

Mepamtin Synthesis Reference

No information avaliable

Mepamtin Molecular Weight

309.469 g/mol

Mepamtin Melting Point

< 25 ^oC

Mepamtin H₂O Solubility

Soluble as HCl salt

Mepamtin State

Liquid

Mepamtin LogP

5.7

Mepamtin Dosage Forms

Tablets (oral, 1 mg)

Mepamtin Indication

Used for the symptomatic treatment of parkinsonism.

Mepamtin Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Mepamtin Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Mepamtin side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Mepamtin Patient Information

Mepamtin Organisms Affected

Humans and other mammals