Metranquil
Brand names,
Metranquil
Analogs
Metranquil
Brand Names Mixture
Metranquil
Chemical_Formula
C20H23NS
Metranquil
RX_link
No information avaliable
Metranquil
fda sheet
Metranquil
msds (material safety sheet)
Metranquil
Synthesis Reference
No information avaliable
Metranquil
Molecular Weight
309.469 g/mol
Metranquil
Melting Point
< 25 oC
Metranquil
H2O Solubility
Soluble as HCl salt
Metranquil
State
Liquid
Metranquil
LogP
5.7
Metranquil
Dosage Forms
Tablets (oral, 1 mg)
Metranquil
Indication
Used for the symptomatic treatment of parkinsonism.
Metranquil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Metranquil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Metranquil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Metranquil
Patient Information
Metranquil
Organisms Affected
Humans and other mammals