Meprodil
Brand names,
Meprodil
Analogs
Meprodil
Brand Names Mixture
Meprodil
Chemical_Formula
C20H23NS
Meprodil
RX_link
No information avaliable
Meprodil
fda sheet
Meprodil
msds (material safety sheet)
Meprodil
Synthesis Reference
No information avaliable
Meprodil
Molecular Weight
309.469 g/mol
Meprodil
Melting Point
< 25 oC
Meprodil
H2O Solubility
Soluble as HCl salt
Meprodil
State
Liquid
Meprodil
LogP
5.7
Meprodil
Dosage Forms
Tablets (oral, 1 mg)
Meprodil
Indication
Used for the symptomatic treatment of parkinsonism.
Meprodil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprodil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprodil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprodil
Patient Information
Meprodil
Organisms Affected
Humans and other mammals