Trelmar
Brand names,
Trelmar
Analogs
Trelmar
Brand Names Mixture
Trelmar
Chemical_Formula
C20H23NS
Trelmar
RX_link
No information avaliable
Trelmar
fda sheet
Trelmar
msds (material safety sheet)
Trelmar
Synthesis Reference
No information avaliable
Trelmar
Molecular Weight
309.469 g/mol
Trelmar
Melting Point
< 25 oC
Trelmar
H2O Solubility
Soluble as HCl salt
Trelmar
State
Liquid
Trelmar
LogP
5.7
Trelmar
Dosage Forms
Tablets (oral, 1 mg)
Trelmar
Indication
Used for the symptomatic treatment of parkinsonism.
Trelmar
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Trelmar
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Trelmar
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Trelmar
Patient Information
Trelmar
Organisms Affected
Humans and other mammals