Mepriam
Brand names,
Mepriam
Analogs
Mepriam
Brand Names Mixture
Mepriam
Chemical_Formula
C20H23NS
Mepriam
RX_link
No information avaliable
Mepriam
fda sheet
Mepriam
msds (material safety sheet)
Mepriam
Synthesis Reference
No information avaliable
Mepriam
Molecular Weight
309.469 g/mol
Mepriam
Melting Point
< 25 oC
Mepriam
H2O Solubility
Soluble as HCl salt
Mepriam
State
Liquid
Mepriam
LogP
5.7
Mepriam
Dosage Forms
Tablets (oral, 1 mg)
Mepriam
Indication
Used for the symptomatic treatment of parkinsonism.
Mepriam
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mepriam
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mepriam
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mepriam
Patient Information
Mepriam
Organisms Affected
Humans and other mammals