Meprotanum
Brand names,
Meprotanum
Analogs
Meprotanum
Brand Names Mixture
Meprotanum
Chemical_Formula
C20H23NS
Meprotanum
RX_link
No information avaliable
Meprotanum
fda sheet
Meprotanum
msds (material safety sheet)
Meprotanum
Synthesis Reference
No information avaliable
Meprotanum
Molecular Weight
309.469 g/mol
Meprotanum
Melting Point
< 25 oC
Meprotanum
H2O Solubility
Soluble as HCl salt
Meprotanum
State
Liquid
Meprotanum
LogP
5.7
Meprotanum
Dosage Forms
Tablets (oral, 1 mg)
Meprotanum
Indication
Used for the symptomatic treatment of parkinsonism.
Meprotanum
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprotanum
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprotanum
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprotanum
Patient Information
Meprotanum
Organisms Affected
Humans and other mammals