Diron
Brand names,
Diron
Analogs
Diron
Brand Names Mixture
Diron
Chemical_Formula
C20H23NS
Diron
RX_link
No information avaliable
Diron
fda sheet
Diron
msds (material safety sheet)
Diron
Synthesis Reference
No information avaliable
Diron
Molecular Weight
309.469 g/mol
Diron
Melting Point
< 25 oC
Diron
H2O Solubility
Soluble as HCl salt
Diron
State
Liquid
Diron
LogP
5.7
Diron
Dosage Forms
Tablets (oral, 1 mg)
Diron
Indication
Used for the symptomatic treatment of parkinsonism.
Diron
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Diron
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Diron
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Diron
Patient Information
Diron
Organisms Affected
Humans and other mammals