Meptranactylmilprem
Brand names,
Meptranactylmilprem
Analogs
Meptranactylmilprem
Brand Names Mixture
Meptranactylmilprem
Chemical_Formula
C20H23NS
Meptranactylmilprem
RX_link
No information avaliable
Meptranactylmilprem
fda sheet
Meptranactylmilprem
msds (material safety sheet)
Meptranactylmilprem
Synthesis Reference
No information avaliable
Meptranactylmilprem
Molecular Weight
309.469 g/mol
Meptranactylmilprem
Melting Point
< 25 oC
Meptranactylmilprem
H2O Solubility
Soluble as HCl salt
Meptranactylmilprem
State
Liquid
Meptranactylmilprem
LogP
5.7
Meptranactylmilprem
Dosage Forms
Tablets (oral, 1 mg)
Meptranactylmilprem
Indication
Used for the symptomatic treatment of parkinsonism.
Meptranactylmilprem
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meptranactylmilprem
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meptranactylmilprem
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meptranactylmilprem
Patient Information
Meptranactylmilprem
Organisms Affected
Humans and other mammals