Optarket
Brand names,
Optarket
Analogs
Optarket
Brand Names Mixture
Optarket
Chemical_Formula
C20H23NS
Optarket
RX_link
No information avaliable
Optarket
fda sheet
Optarket
msds (material safety sheet)
Optarket
Synthesis Reference
No information avaliable
Optarket
Molecular Weight
309.469 g/mol
Optarket
Melting Point
< 25 oC
Optarket
H2O Solubility
Soluble as HCl salt
Optarket
State
Liquid
Optarket
LogP
5.7
Optarket
Dosage Forms
Tablets (oral, 1 mg)
Optarket
Indication
Used for the symptomatic treatment of parkinsonism.
Optarket
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Optarket
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Optarket
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Optarket
Patient Information
Optarket
Organisms Affected
Humans and other mammals