Rastenil
Brand names,
Rastenil
Analogs
Rastenil
Brand Names Mixture
Rastenil
Chemical_Formula
C20H23NS
Rastenil
RX_link
No information avaliable
Rastenil
fda sheet
Rastenil
msds (material safety sheet)
Rastenil
Synthesis Reference
No information avaliable
Rastenil
Molecular Weight
309.469 g/mol
Rastenil
Melting Point
< 25 oC
Rastenil
H2O Solubility
Soluble as HCl salt
Rastenil
State
Liquid
Rastenil
LogP
5.7
Rastenil
Dosage Forms
Tablets (oral, 1 mg)
Rastenil
Indication
Used for the symptomatic treatment of parkinsonism.
Rastenil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Rastenil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Rastenil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Rastenil
Patient Information
Rastenil
Organisms Affected
Humans and other mammals