Sedazil
Brand names,
Sedazil
Analogs
Sedazil
Brand Names Mixture
Sedazil
Chemical_Formula
C20H23NS
Sedazil
RX_link
No information avaliable
Sedazil
fda sheet
Sedazil
msds (material safety sheet)
Sedazil
Synthesis Reference
No information avaliable
Sedazil
Molecular Weight
309.469 g/mol
Sedazil
Melting Point
< 25 oC
Sedazil
H2O Solubility
Soluble as HCl salt
Sedazil
State
Liquid
Sedazil
LogP
5.7
Sedazil
Dosage Forms
Tablets (oral, 1 mg)
Sedazil
Indication
Used for the symptomatic treatment of parkinsonism.
Sedazil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Sedazil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Sedazil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Sedazil
Patient Information
Sedazil
Organisms Affected
Humans and other mammals