Dicandiol
Brand names,
Dicandiol
Analogs
Dicandiol
Brand Names Mixture
Dicandiol
Chemical_Formula
C20H23NS
Dicandiol
RX_link
No information avaliable
Dicandiol
fda sheet
Dicandiol
msds (material safety sheet)
Dicandiol
Synthesis Reference
No information avaliable
Dicandiol
Molecular Weight
309.469 g/mol
Dicandiol
Melting Point
< 25 oC
Dicandiol
H2O Solubility
Soluble as HCl salt
Dicandiol
State
Liquid
Dicandiol
LogP
5.7
Dicandiol
Dosage Forms
Tablets (oral, 1 mg)
Dicandiol
Indication
Used for the symptomatic treatment of parkinsonism.
Dicandiol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Dicandiol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Dicandiol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Dicandiol
Patient Information
Dicandiol
Organisms Affected
Humans and other mammals