Procalmadol
Brand names,
Procalmadol
Analogs
Procalmadol
Brand Names Mixture
Procalmadol
Chemical_Formula
C20H23NS
Procalmadol
RX_link
No information avaliable
Procalmadol
fda sheet
Procalmadol
msds (material safety sheet)
Procalmadol
Synthesis Reference
No information avaliable
Procalmadol
Molecular Weight
309.469 g/mol
Procalmadol
Melting Point
< 25 oC
Procalmadol
H2O Solubility
Soluble as HCl salt
Procalmadol
State
Liquid
Procalmadol
LogP
5.7
Procalmadol
Dosage Forms
Tablets (oral, 1 mg)
Procalmadol
Indication
Used for the symptomatic treatment of parkinsonism.
Procalmadol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Procalmadol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Procalmadol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Procalmadol
Patient Information
Procalmadol
Organisms Affected
Humans and other mammals