Solevione anastress
Brand names,
Solevione anastress
Analogs
Solevione anastress
Brand Names Mixture
Solevione anastress
Chemical_Formula
C20H23NS
Solevione anastress
RX_link
No information avaliable
Solevione anastress
fda sheet
Solevione anastress
msds (material safety sheet)
Solevione anastress
Synthesis Reference
No information avaliable
Solevione anastress
Molecular Weight
309.469 g/mol
Solevione anastress
Melting Point
< 25 oC
Solevione anastress
H2O Solubility
Soluble as HCl salt
Solevione anastress
State
Liquid
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LogP
5.7
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Dosage Forms
Tablets (oral, 1 mg)
Solevione anastress
Indication
Used for the symptomatic treatment of parkinsonism.
Solevione anastress
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Solevione anastress
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Solevione anastress
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Solevione anastress
Patient Information
Solevione anastress
Organisms Affected
Humans and other mammals