Seril
Brand names,
Seril
Analogs
Seril
Brand Names Mixture
Seril
Chemical_Formula
C20H23NS
Seril
RX_link
No information avaliable
Seril
fda sheet
Seril
msds (material safety sheet)
Seril
Synthesis Reference
No information avaliable
Seril
Molecular Weight
309.469 g/mol
Seril
Melting Point
< 25 oC
Seril
H2O Solubility
Soluble as HCl salt
Seril
State
Liquid
Seril
LogP
5.7
Seril
Dosage Forms
Tablets (oral, 1 mg)
Seril
Indication
Used for the symptomatic treatment of parkinsonism.
Seril
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Seril
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Seril
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Seril
Patient Information
Seril
Organisms Affected
Humans and other mammals