Lepetown
Brand names,
Lepetown
Analogs
Lepetown
Brand Names Mixture
Lepetown
Chemical_Formula
C20H23NS
Lepetown
RX_link
No information avaliable
Lepetown
fda sheet
Lepetown
msds (material safety sheet)
Lepetown
Synthesis Reference
No information avaliable
Lepetown
Molecular Weight
309.469 g/mol
Lepetown
Melting Point
< 25 oC
Lepetown
H2O Solubility
Soluble as HCl salt
Lepetown
State
Liquid
Lepetown
LogP
5.7
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Dosage Forms
Tablets (oral, 1 mg)
Lepetown
Indication
Used for the symptomatic treatment of parkinsonism.
Lepetown
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Lepetown
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Lepetown
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Lepetown
Patient Information
Lepetown
Organisms Affected
Humans and other mammals