Orolevol
Brand names,
Orolevol
Analogs
Orolevol
Brand Names Mixture
Orolevol
Chemical_Formula
C20H23NS
Orolevol
RX_link
No information avaliable
Orolevol
fda sheet
Orolevol
msds (material safety sheet)
Orolevol
Synthesis Reference
No information avaliable
Orolevol
Molecular Weight
309.469 g/mol
Orolevol
Melting Point
< 25 oC
Orolevol
H2O Solubility
Soluble as HCl salt
Orolevol
State
Liquid
Orolevol
LogP
5.7
Orolevol
Dosage Forms
Tablets (oral, 1 mg)
Orolevol
Indication
Used for the symptomatic treatment of parkinsonism.
Orolevol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Orolevol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Orolevol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Orolevol
Patient Information
Orolevol
Organisms Affected
Humans and other mammals