Quaname
Brand names,
Quaname
Analogs
Quaname
Brand Names Mixture
Quaname
Chemical_Formula
C20H23NS
Quaname
RX_link
No information avaliable
Quaname
fda sheet
Quaname
msds (material safety sheet)
Quaname
Synthesis Reference
No information avaliable
Quaname
Molecular Weight
309.469 g/mol
Quaname
Melting Point
< 25 oC
Quaname
H2O Solubility
Soluble as HCl salt
Quaname
State
Liquid
Quaname
LogP
5.7
Quaname
Dosage Forms
Tablets (oral, 1 mg)
Quaname
Indication
Used for the symptomatic treatment of parkinsonism.
Quaname
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Quaname
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Quaname
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Quaname
Patient Information
Quaname
Organisms Affected
Humans and other mammals