Libiolan
Brand names,
Libiolan
Analogs
Libiolan
Brand Names Mixture
Libiolan
Chemical_Formula
C20H23NS
Libiolan
RX_link
No information avaliable
Libiolan
fda sheet
Libiolan
msds (material safety sheet)
Libiolan
Synthesis Reference
No information avaliable
Libiolan
Molecular Weight
309.469 g/mol
Libiolan
Melting Point
< 25 oC
Libiolan
H2O Solubility
Soluble as HCl salt
Libiolan
State
Liquid
Libiolan
LogP
5.7
Libiolan
Dosage Forms
Tablets (oral, 1 mg)
Libiolan
Indication
Used for the symptomatic treatment of parkinsonism.
Libiolan
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Libiolan
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Libiolan
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Libiolan
Patient Information
Libiolan
Organisms Affected
Humans and other mammals