Arpon
Brand names,
Arpon
Analogs
Arpon
Brand Names Mixture
Arpon
Chemical_Formula
C20H23NS
Arpon
RX_link
No information avaliable
Arpon
fda sheet
Arpon
msds (material safety sheet)
Arpon
Synthesis Reference
No information avaliable
Arpon
Molecular Weight
309.469 g/mol
Arpon
Melting Point
< 25 oC
Arpon
H2O Solubility
Soluble as HCl salt
Arpon
State
Liquid
Arpon
LogP
5.7
Arpon
Dosage Forms
Tablets (oral, 1 mg)
Arpon
Indication
Used for the symptomatic treatment of parkinsonism.
Arpon
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Arpon
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Arpon
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Arpon
Patient Information
Arpon
Organisms Affected
Humans and other mammals