Equanil
Brand names,
Equanil
Analogs
Equanil
Brand Names Mixture
Equanil
Chemical_Formula
C20H23NS
Equanil
RX_link
No information avaliable
Equanil
fda sheet
Equanil
msds (material safety sheet)
Equanil
Synthesis Reference
No information avaliable
Equanil
Molecular Weight
309.469 g/mol
Equanil
Melting Point
< 25 oC
Equanil
H2O Solubility
Soluble as HCl salt
Equanil
State
Liquid
Equanil
LogP
5.7
Equanil
Dosage Forms
Tablets (oral, 1 mg)
Equanil
Indication
Used for the symptomatic treatment of parkinsonism.
Equanil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Equanil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Equanil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Equanil
Patient Information
Equanil
Organisms Affected
Humans and other mammals