Cirponyl
Brand names,
Cirponyl
Analogs
Cirponyl
Brand Names Mixture
Cirponyl
Chemical_Formula
C20H23NS
Cirponyl
RX_link
No information avaliable
Cirponyl
fda sheet
Cirponyl
msds (material safety sheet)
Cirponyl
Synthesis Reference
No information avaliable
Cirponyl
Molecular Weight
309.469 g/mol
Cirponyl
Melting Point
< 25 oC
Cirponyl
H2O Solubility
Soluble as HCl salt
Cirponyl
State
Liquid
Cirponyl
LogP
5.7
Cirponyl
Dosage Forms
Tablets (oral, 1 mg)
Cirponyl
Indication
Used for the symptomatic treatment of parkinsonism.
Cirponyl
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Cirponyl
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Cirponyl
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Cirponyl
Patient Information
Cirponyl
Organisms Affected
Humans and other mammals