Aneusral
Brand names,
Aneusral
Analogs
Aneusral
Brand Names Mixture
Aneusral
Chemical_Formula
C20H23NS
Aneusral
RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
Aneusral
Synthesis Reference
No information avaliable
Aneusral
Molecular Weight
309.469 g/mol
Aneusral
Melting Point
< 25 oC
Aneusral
H2O Solubility
Soluble as HCl salt
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State
Liquid
Aneusral
LogP
5.7
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Dosage Forms
Tablets (oral, 1 mg)
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Indication
Used for the symptomatic treatment of parkinsonism.
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Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Aneusral
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Aneusral
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
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Patient Information
Aneusral
Organisms Affected
Humans and other mammals