Meprotabs
Brand names,
Meprotabs
Analogs
Meprotabs
Brand Names Mixture
Meprotabs
Chemical_Formula
C20H23NS
Meprotabs
RX_link
No information avaliable
Meprotabs
fda sheet
Meprotabs
msds (material safety sheet)
Meprotabs
Synthesis Reference
No information avaliable
Meprotabs
Molecular Weight
309.469 g/mol
Meprotabs
Melting Point
< 25 oC
Meprotabs
H2O Solubility
Soluble as HCl salt
Meprotabs
State
Liquid
Meprotabs
LogP
5.7
Meprotabs
Dosage Forms
Tablets (oral, 1 mg)
Meprotabs
Indication
Used for the symptomatic treatment of parkinsonism.
Meprotabs
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprotabs
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprotabs
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprotabs
Patient Information
Meprotabs
Organisms Affected
Humans and other mammals