Hartol
Brand names,
Hartol
Analogs
Hartol
Brand Names Mixture
Hartol
Chemical_Formula
C20H23NS
Hartol
RX_link
No information avaliable
Hartol
fda sheet
Hartol
msds (material safety sheet)
Hartol
Synthesis Reference
No information avaliable
Hartol
Molecular Weight
309.469 g/mol
Hartol
Melting Point
< 25 oC
Hartol
H2O Solubility
Soluble as HCl salt
Hartol
State
Liquid
Hartol
LogP
5.7
Hartol
Dosage Forms
Tablets (oral, 1 mg)
Hartol
Indication
Used for the symptomatic treatment of parkinsonism.
Hartol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Hartol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Hartol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Hartol
Patient Information
Hartol
Organisms Affected
Humans and other mammals