Procalmidol
Brand names,
Procalmidol
Analogs
Procalmidol
Brand Names Mixture
Procalmidol
Chemical_Formula
C20H23NS
Procalmidol
RX_link
No information avaliable
Procalmidol
fda sheet
Procalmidol
msds (material safety sheet)
Procalmidol
Synthesis Reference
No information avaliable
Procalmidol
Molecular Weight
309.469 g/mol
Procalmidol
Melting Point
< 25 oC
Procalmidol
H2O Solubility
Soluble as HCl salt
Procalmidol
State
Liquid
Procalmidol
LogP
5.7
Procalmidol
Dosage Forms
Tablets (oral, 1 mg)
Procalmidol
Indication
Used for the symptomatic treatment of parkinsonism.
Procalmidol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Procalmidol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Procalmidol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Procalmidol
Patient Information
Procalmidol
Organisms Affected
Humans and other mammals