Meprotan

Meprotan Brand names, Meprotan Analogs

Meprotan Brand Names Mixture

No information avaliable

Meprotan Chemical_Formula

C₂₀H₂₃NS

Meprotan RX_link

No information avaliable

Meprotan fda sheet

Meprotan msds (material safety sheet)

Meprotan Synthesis Reference

No information avaliable

Meprotan Molecular Weight

309.469 g/mol

Meprotan Melting Point

< 25 ^oC

Meprotan H₂O Solubility

Soluble as HCl salt

Meprotan State

Liquid

Meprotan LogP

5.7

Meprotan Dosage Forms

Tablets (oral, 1 mg)

Meprotan Indication

Used for the symptomatic treatment of parkinsonism.

Meprotan Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Meprotan Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Meprotan side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Meprotan Patient Information

Meprotan Organisms Affected

Humans and other mammals