Probamyl

Probamyl Brand names, Probamyl Analogs

Probamyl Brand Names Mixture

No information avaliable

Probamyl Chemical_Formula

C₂₀H₂₃NS

Probamyl RX_link

No information avaliable

Probamyl fda sheet

Probamyl msds (material safety sheet)

Probamyl Synthesis Reference

No information avaliable

Probamyl Molecular Weight

309.469 g/mol

Probamyl Melting Point

< 25 ^oC

Probamyl H₂O Solubility

Soluble as HCl salt

Probamyl State

Liquid

Probamyl LogP

5.7

Probamyl Dosage Forms

Tablets (oral, 1 mg)

Probamyl Indication

Used for the symptomatic treatment of parkinsonism.

Probamyl Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Probamyl Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Probamyl side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Probamyl Patient Information

Probamyl Organisms Affected

Humans and other mammals