Tranquilate

Tranquilate Brand names, Tranquilate Analogs

Tranquilate Brand Names Mixture

No information avaliable

Tranquilate Chemical_Formula

C₂₀H₂₃NS

Tranquilate RX_link

No information avaliable

Tranquilate fda sheet

Tranquilate msds (material safety sheet)

Tranquilate Synthesis Reference

No information avaliable

Tranquilate Molecular Weight

309.469 g/mol

Tranquilate Melting Point

< 25 ^oC

Tranquilate H₂O Solubility

Soluble as HCl salt

Tranquilate State

Liquid

Tranquilate LogP

5.7

Tranquilate Dosage Forms

Tablets (oral, 1 mg)

Tranquilate Indication

Used for the symptomatic treatment of parkinsonism.

Tranquilate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Tranquilate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Tranquilate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Tranquilate Patient Information

Tranquilate Organisms Affected

Humans and other mammals