Appetrol
Brand names,
Appetrol
Analogs
Appetrol
Brand Names Mixture
Appetrol
Chemical_Formula
C20H23NS
Appetrol
RX_link
No information avaliable
Appetrol
fda sheet
Appetrol
msds (material safety sheet)
Appetrol
Synthesis Reference
No information avaliable
Appetrol
Molecular Weight
309.469 g/mol
Appetrol
Melting Point
< 25 oC
Appetrol
H2O Solubility
Soluble as HCl salt
Appetrol
State
Liquid
Appetrol
LogP
5.7
Appetrol
Dosage Forms
Tablets (oral, 1 mg)
Appetrol
Indication
Used for the symptomatic treatment of parkinsonism.
Appetrol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Appetrol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Appetrol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Appetrol
Patient Information
Appetrol
Organisms Affected
Humans and other mammals